MCF2L protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Experiments

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[Homology]

Score

MCF2L

MCF.2 cell line derived transforming sequence like. (1124 aa)

Predicted Functional Partners:

ENSNVIP00000003529

0.901

CDC42

0.901

ENSNVIP00000030096

0.901

IL1RAPL1

0.751

RAC1

0.746

RAC3

0.746

RAC2

0.743

ENSNVIP00000002228

0.708

ENSNVIP00000004345

0.708

RHOB

0.708

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSNVIP00000002228	ENSNVIP00000029236	ENSNVIP00000002228	Cell division cycle 42.	annotation not available	0.564
CDC42	ENSNVIP00000004345	ENSNVIP00000029236	ENSNVIP00000004345	Cell division cycle 42.	annotation not available	0.564
CDC42	MCF2L	ENSNVIP00000029236	ENSNVIP00000001127	Cell division cycle 42.	MCF.2 cell line derived transforming sequence like.	0.901
CDC42	RAC1	ENSNVIP00000029236	ENSNVIP00000007750	Cell division cycle 42.	Rac family small GTPase 1.	0.792
CDC42	RAC2	ENSNVIP00000029236	ENSNVIP00000003849	Cell division cycle 42.	Rac family small GTPase 2.	0.837
CDC42	RAC3	ENSNVIP00000029236	ENSNVIP00000021542	Cell division cycle 42.	Rac family small GTPase 3.	0.780
CDC42	RHOB	ENSNVIP00000029236	ENSNVIP00000016501	Cell division cycle 42.	Ras homolog family member B.	0.564
ENSNVIP00000002228	CDC42	ENSNVIP00000002228	ENSNVIP00000029236	annotation not available	Cell division cycle 42.	0.564
ENSNVIP00000002228	ENSNVIP00000003529	ENSNVIP00000002228	ENSNVIP00000003529	annotation not available	annotation not available	0.564
ENSNVIP00000002228	ENSNVIP00000030096	ENSNVIP00000002228	ENSNVIP00000030096	annotation not available	annotation not available	0.564
ENSNVIP00000002228	MCF2L	ENSNVIP00000002228	ENSNVIP00000001127	annotation not available	MCF.2 cell line derived transforming sequence like.	0.708
ENSNVIP00000002228	RAC1	ENSNVIP00000002228	ENSNVIP00000007750	annotation not available	Rac family small GTPase 1.	0.636
ENSNVIP00000002228	RAC2	ENSNVIP00000002228	ENSNVIP00000003849	annotation not available	Rac family small GTPase 2.	0.680
ENSNVIP00000002228	RAC3	ENSNVIP00000002228	ENSNVIP00000021542	annotation not available	Rac family small GTPase 3.	0.636
ENSNVIP00000003529	ENSNVIP00000002228	ENSNVIP00000003529	ENSNVIP00000002228	annotation not available	annotation not available	0.564
ENSNVIP00000003529	ENSNVIP00000004345	ENSNVIP00000003529	ENSNVIP00000004345	annotation not available	annotation not available	0.773
ENSNVIP00000003529	MCF2L	ENSNVIP00000003529	ENSNVIP00000001127	annotation not available	MCF.2 cell line derived transforming sequence like.	0.901
ENSNVIP00000003529	RAC1	ENSNVIP00000003529	ENSNVIP00000007750	annotation not available	Rac family small GTPase 1.	0.792
ENSNVIP00000003529	RAC2	ENSNVIP00000003529	ENSNVIP00000003849	annotation not available	Rac family small GTPase 2.	0.837
ENSNVIP00000003529	RAC3	ENSNVIP00000003529	ENSNVIP00000021542	annotation not available	Rac family small GTPase 3.	0.780