Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESPL1Extra spindle pole bodies like 1, separase. (1949 aa)    
Predicted Functional Partners:
PLK1
Polo like kinase 1.
   
 0.992
ENSNVIP00000006831
annotation not available
   
 0.988
ENSNVIP00000018285
annotation not available
   
 0.988
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.987
RAD21
RAD21 cohesin complex component.
   
 0.983
REC8
REC8 meiotic recombination protein.
   
 0.982
SMC3
Structural maintenance of chromosomes 3.
   
 0.975
ENSNVIP00000020897
annotation not available
   
 
 0.974
SMC1B
Structural maintenance of chromosomes 1B.
   
 0.972
SMC1A
Structural maintenance of chromosomes 1A.
   
 0.972
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.