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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFDNAfadin, adherens junction formation factor. (1833 aa)    
Predicted Functional Partners:
NECTIN2
Nectin cell adhesion molecule 2.
    
 0.988
NECTIN3
Nectin cell adhesion molecule 3.
    
 0.986
ENSNVIP00000013007
annotation not available
   
 0.978
TJP1
Tight junction protein 1.
   
 0.977
NECTIN1
Nectin cell adhesion molecule 1.
    
 0.974
ENSNVIP00000001371
RAP1A, member of RAS oncogene family.
    
 0.964
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.963
F11R
F11 receptor.
    
 0.962
CTNND1
Catenin delta 1.
     
 0.959
ENSNVIP00000001458
KRAS proto-oncogene, GTPase.
    
 0.953
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.