Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPM1DProtein phosphatase, Mg2+/Mn2+ dependent 1D. (606 aa)    
Predicted Functional Partners:
TP53
Tumor protein p53.
    
 
 0.937
CBFB
Core-binding factor subunit beta.
     
 0.792
ENSNVIP00000005200
Checkpoint kinase 2.
    
 
 0.789
NME8
NME/NM23 family member 8.
   
 0.674
WDR90
WD repeat domain 90.
    
   0.628
ENSNVIP00000001273
Amyloid beta precursor protein binding protein 2.
   
 
 0.624
TP53BP1
Tumor protein p53 binding protein 1.
    
 
 0.602
RUNX1
RUNX family transcription factor 1.
    
 0.601
RUNX2
RUNX family transcription factor 2.
    
 0.601
RUNX3
RUNX family transcription factor 3.
    
 0.601
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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