Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
GAB2GRB2 associated binding protein 2. (677 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.931
ENSNVIP00000009278
annotation not available
     
 0.904
LYN
LYN proto-oncogene, Src family tyrosine kinase.
     
 0.904
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
     
 0.904
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
     
 0.894
PDGFRB
Platelet derived growth factor receptor beta.
     
 0.889
PLCG2
Phospholipase C gamma 2.
     
 0.889
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
   
 
 0.888
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 
 0.888
PDGFRA
Platelet derived growth factor receptor alpha.
     
 0.888
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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