Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSNVIP00000001458KRAS proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.985
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.982
EGFR
Epidermal growth factor receptor.
    
 0.973
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.972
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.971
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.969
ENSNVIP00000025242
annotation not available
   
 0.965
NF1
Neurofibromin 1.
    
 0.964
ENSNVIP00000013070
annotation not available
    
 0.961
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
   
 0.960
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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