Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDGFRBPlatelet derived growth factor receptor beta. (1112 aa)    
Predicted Functional Partners:
ENSNVIP00000001736
Platelet derived growth factor subunit B.
   
 0.998
PLCG1
Phospholipase C gamma 1.
    
 0.993
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.993
PDGFRA
Platelet derived growth factor receptor alpha.
   
 0.991
GRB2
Growth factor receptor bound protein 2.
    
 0.986
ENSNVIP00000009278
annotation not available
   
 0.984
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
   
 0.984
EGFR
Epidermal growth factor receptor.
   
 0.982
PLCG2
Phospholipase C gamma 2.
    
 0.980
RASA1
RAS p21 protein activator 1.
   
 0.973
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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