STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SP1Sp1 transcription factor. (716 aa)    
Predicted Functional Partners:
ESR1
Estrogen receptor 1.
    
 0.993
EP300
E1A binding protein p300.
   
 0.991
JUN
Jun proto-oncogene, AP-1 transcription factor subunit.
    
 0.983
CREBBP
CREB binding protein.
   
 0.980
ESR2
Estrogen receptor 2.
    
 0.971
SMAD4
SMAD family member 4.
   
 0.961
TP53
Tumor protein p53.
   
 0.957
MAPK3
Mitogen-activated protein kinase 3.
    
 0.956
MAPK1
Mitogen-activated protein kinase 1.
    
 0.956
AR
Androgen receptor.
    
 0.954
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.