Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF7Rho guanine nucleotide exchange factor 7. (833 aa)    
Predicted Functional Partners:
GIT1
GIT ArfGAP 1.
   
 0.990
PAK2
P21 (RAC1) activated kinase 2.
   
 0.984
PAK1
P21 (RAC1) activated kinase 1.
   
 0.968
PAK3
P21 (RAC1) activated kinase 3.
   
 0.968
GIT2
GIT ArfGAP 2.
   
 0.961
PXN
Paxillin.
    
 0.960
RAC2
Rac family small GTPase 2.
   
 0.950
ENSNVIP00000023038
P21 (RAC1) activated kinase 5.
    
 0.935
PAK6
P21 (RAC1) activated kinase 6.
    
 0.929
CBL
Cbl proto-oncogene.
    
 0.922
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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