STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORL1Sortilin related receptor 1. (2211 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.990
LRPAP1
LDL receptor related protein associated protein 1.
    
 0.957
APLP2
Amyloid beta precursor like protein 2.
    
 0.895
APOE
Apolipoprotein E.
    
 0.884
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.878
ENSNVIP00000003900
annotation not available
    
 
 0.878
NGFR
Nerve growth factor receptor.
    
 0.848
VPS35
VPS35 retromer complex component.
    
 
 0.837
GAK
Cyclin G associated kinase.
   
 0.832
APLP1
Amyloid beta precursor like protein 1.
    
 0.821
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.