THEMIS protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

THEMIS

Thymocyte selection associated. (565 aa)

Predicted Functional Partners:

GRB2

0.784

ENSNVIP00000001677

0.768

ENSNVIP00000032225

0.622

GRAP2

0.618

ENSNVIP00000007493

0.502

NXPH4

0.435

SETX

0.433

ENSNVIP00000025384

0.408

SYT6

0.406

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNVIP00000001677	ENSNVIP00000007493	ENSNVIP00000001677	ENSNVIP00000007493	annotation not available	Linker for activation of T cells.	0.502
ENSNVIP00000001677	ENSNVIP00000025384	ENSNVIP00000001677	ENSNVIP00000025384	annotation not available	Leucine rich repeat transmembrane neuronal 4.	0.408
ENSNVIP00000001677	ENSNVIP00000032225	ENSNVIP00000001677	ENSNVIP00000032225	annotation not available	annotation not available	0.622
ENSNVIP00000001677	GRAP2	ENSNVIP00000001677	ENSNVIP00000001406	annotation not available	GRB2 related adaptor protein 2.	0.618
ENSNVIP00000001677	GRB2	ENSNVIP00000001677	ENSNVIP00000013678	annotation not available	Growth factor receptor bound protein 2.	0.784
ENSNVIP00000001677	NXPH4	ENSNVIP00000001677	ENSNVIP00000009477	annotation not available	Neurexophilin 4.	0.435
ENSNVIP00000001677	SYT6	ENSNVIP00000001677	ENSNVIP00000006270	annotation not available	Synaptotagmin 6.	0.406
ENSNVIP00000001677	THEMIS	ENSNVIP00000001677	ENSNVIP00000001707	annotation not available	Thymocyte selection associated.	0.768
ENSNVIP00000007493	ENSNVIP00000001677	ENSNVIP00000007493	ENSNVIP00000001677	Linker for activation of T cells.	annotation not available	0.502
ENSNVIP00000007493	ENSNVIP00000032225	ENSNVIP00000007493	ENSNVIP00000032225	Linker for activation of T cells.	annotation not available	0.911
ENSNVIP00000007493	GRAP2	ENSNVIP00000007493	ENSNVIP00000001406	Linker for activation of T cells.	GRB2 related adaptor protein 2.	0.987
ENSNVIP00000007493	GRB2	ENSNVIP00000007493	ENSNVIP00000013678	Linker for activation of T cells.	Growth factor receptor bound protein 2.	0.997
ENSNVIP00000007493	THEMIS	ENSNVIP00000007493	ENSNVIP00000001707	Linker for activation of T cells.	Thymocyte selection associated.	0.502
ENSNVIP00000025384	ENSNVIP00000001677	ENSNVIP00000025384	ENSNVIP00000001677	Leucine rich repeat transmembrane neuronal 4.	annotation not available	0.408
ENSNVIP00000025384	THEMIS	ENSNVIP00000025384	ENSNVIP00000001707	Leucine rich repeat transmembrane neuronal 4.	Thymocyte selection associated.	0.408
ENSNVIP00000032225	ENSNVIP00000001677	ENSNVIP00000032225	ENSNVIP00000001677	annotation not available	annotation not available	0.622
ENSNVIP00000032225	ENSNVIP00000007493	ENSNVIP00000032225	ENSNVIP00000007493	annotation not available	Linker for activation of T cells.	0.911
ENSNVIP00000032225	GRB2	ENSNVIP00000032225	ENSNVIP00000013678	annotation not available	Growth factor receptor bound protein 2.	0.729
ENSNVIP00000032225	THEMIS	ENSNVIP00000032225	ENSNVIP00000001707	annotation not available	Thymocyte selection associated.	0.622
GRAP2	ENSNVIP00000001677	ENSNVIP00000001406	ENSNVIP00000001677	GRB2 related adaptor protein 2.	annotation not available	0.618