STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SC5Dsterol-C5-desaturase. (299 aa)    
Predicted Functional Partners:
DHCR7
7-dehydrocholesterol reductase.
   
 0.990
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 0.986
FAXDC2
Fatty acid hydroxylase domain containing 2.
   
 0.977
MSMO1
Methylsterol monooxygenase 1.
   
 0.977
CH25H
Cholesterol 25-hydroxylase.
   
 0.977
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 0.975
CYP51A1
Cytochrome P450 family 51 subfamily A member 1.
   
 0.972
ENSNVIP00000008158
annotation not available
   
 
 0.969
TM7SF2
Transmembrane 7 superfamily member 2.
   
 0.959
DHCR24
24-dehydrocholesterol reductase.
   
 
 0.950
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.