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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPARGC1BPPARG coactivator 1 beta. (1029 aa)    
Predicted Functional Partners:
SREBF1
Sterol regulatory element binding transcription factor 1.
    
 0.957
MLXIP
MLX interacting protein.
     
 0.944
MLXIPL
MLX interacting protein like.
     
 0.938
DNA2
DNA replication helicase/nuclease 2.
      
 0.811
ESRRA
Estrogen related receptor alpha.
    
 0.806
NCBP1
Nuclear cap binding protein subunit 1.
    
   0.751
ENSNVIP00000029825
Nuclear respiratory factor 1.
     
 0.740
SREBF2
Sterol regulatory element binding transcription factor 2.
    
 0.599
NCBP2
Nuclear cap binding protein subunit 2.
    
 
 0.572
NCBP2L
Nuclear cap binding protein subunit 2 like.
    
 
 0.572
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.