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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF146Ring finger protein 146. (360 aa)    
Predicted Functional Partners:
TNKS
Tankyrase.
    
 0.975
TNKS2
Tankyrase 2.
    
 0.941
ENSNVIP00000030368
Ubiquitin conjugating enzyme E2 D1.
   
   0.878
PARP1
poly(ADP-ribose) polymerase 1.
    
 
 0.785
ANK1
Ankyrin 1.
    
 0.775
ANK3
Ankyrin 3.
    
 0.775
ANKDD1B
Ankyrin repeat and death domain containing 1B.
    
 0.775
ANK2
Ankyrin 2.
    
 0.775
ENSNVIP00000019428
poly(ADP-ribose) polymerase 2.
    
 
 0.772
AXIN1
Axin 1.
    
 0.742
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.