STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K15Mitogen-activated protein kinase kinase kinase 15. (1307 aa)    
Predicted Functional Partners:
DAXX
Death domain associated protein.
    
 0.825
MAP2K4
Mitogen-activated protein kinase kinase 4.
    
 0.816
ENSNVIP00000013359
TNF receptor associated factor 6.
    
 0.706
MAP2K3
Mitogen-activated protein kinase kinase 3.
    
 0.696
MAP2K6
Mitogen-activated protein kinase kinase 6.
    
 0.696
ENSNVIP00000004447
Thioredoxin 2.
    
 0.676
TXN
Thioredoxin.
    
 0.628
TXNDC8
Thioredoxin domain containing 8.
    
 0.628
ENSNVIP00000012881
annotation not available
    
 0.628
MOSPD2
Motile sperm domain containing 2.
    
   0.627
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.