Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAPKAPK3MAPK activated protein kinase 3. (384 aa)    
Predicted Functional Partners:
MAPKAPK2
MAPK activated protein kinase 2.
   
  0.997
MAPK11
Mitogen-activated protein kinase 11.
  
0.973
MAPK14
Mitogen-activated protein kinase 14.
  
0.973
HSPB1
Heat shock protein family B (small) member 1.
    
 0.966
ENSNVIP00000031937
annotation not available
    
 0.966
MAPK13
Mitogen-activated protein kinase 13.
  
0.964
MAPK12
Mitogen-activated protein kinase 12.
   
 0.958
ENSNVIP00000018933
annotation not available
   
 0.902
ATF4
Activating transcription factor 4.
     
 0.883
ENSNVIP00000009079
Lymphocyte specific protein 1.
    
 0.804
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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