STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1198 aa)    
Predicted Functional Partners:
BRCA1
BRCA1 DNA repair associated.
   
 0.983
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.980
ENSNVIP00000032370
mutL homolog 1.
   
 0.974
PMS2
PMS1 homolog 2, mismatch repair system component.
   
 0.973
BARD1
BRCA1 associated RING domain 1.
   
 0.969
MRE11
MRE11 homolog, double strand break repair nuclease.
   
 0.921
BRCA2
BRCA2 DNA repair associated.
   
 0.894
PALB2
Partner and localizer of BRCA2.
   
 0.878
WRN
WRN RecQ like helicase.
  
 0.876
ENSNVIP00000006977
SMC5-SMC6 complex localization factor 1.
   
 0.862
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.