Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSNVIP00000002161Cyclin dependent kinase 5. (292 aa)    
Predicted Functional Partners:
MAPT
Microtubule associated protein tau.
    
 0.996
ENSNVIP00000025243
Cyclin dependent kinase 5 regulatory subunit 1.
    
 0.987
CDK5R2
Cyclin dependent kinase 5 regulatory subunit 2.
    
 0.987
PPP1R1B
Protein phosphatase 1 regulatory inhibitor subunit 1B.
    
 0.983
CABLES1
Cdk5 and Abl enzyme substrate 1.
    
 0.979
MAP2
Microtubule associated protein 2.
    
 0.975
DLG4
Discs large MAGUK scaffold protein 4.
    
 0.957
TP53
Tumor protein p53.
    
 0.957
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 
 0.942
C2CD5
C2 calcium dependent domain containing 5.
    
 
 0.938
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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