close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)    
Predicted Functional Partners:
NOTCH4
Notch receptor 4.
   
 0.565
DLL4
Delta like canonical Notch ligand 4.
    
 
 0.558
ENSNVIP00000001898
annotation not available
    
 
 0.491
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.483
NOTCH1
Notch receptor 1.
    
 0.481
JAG1
Jagged canonical Notch ligand 1.
    
 
 0.470
NOTCH3
Notch receptor 3.
    
 0.442
NOTCH2
Notch receptor 2.
    
 0.431
ENSNVIP00000002095
annotation not available
    
 
 0.425
ATOH1
Atonal bHLH transcription factor 1.
    
 
 0.420
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.