Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
    
 0.777
PGGT1B
Protein geranylgeranyltransferase type I subunit beta.
    
 
 0.685
HES1
Hes family bHLH transcription factor 1.
    
 0.660
IST1
IST1 factor associated with ESCRT-III.
    
   0.628
NOTCH4
Notch receptor 4.
   
 0.628
ARL10
ADP ribosylation factor like GTPase 10.
    
   0.628
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.605
ENSNVIP00000018633
Hes related family bHLH transcription factor with YRPW motif like.
     
  0.599
FANCM
FA complementation group M.
     
  0.593
HES2
Hes family bHLH transcription factor 2.
    
 0.556
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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