Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPTBN1Spectrin beta, non-erythrocytic 1. (2364 aa)    
Predicted Functional Partners:
SPTAN1
Spectrin alpha, non-erythrocytic 1.
   
 0.939
SPTA1
Spectrin alpha, erythrocytic 1.
   
0.886
SPTBN2
Spectrin beta, non-erythrocytic 2.
  
 
0.864
ENSNVIP00000004080
Adducin 2.
    
 
 0.698
DMTN
Dematin actin binding protein.
   
 
 0.643
ANK1
Ankyrin 1.
   
 0.603
ANK3
Ankyrin 3.
   
 0.603
ANK2
Ankyrin 2.
   
 0.603
NF2
Neurofibromin 2.
    
 0.554
SPTB
Spectrin beta, erythrocytic.
  
 
 
0.551
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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