Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MITFMelanocyte inducing transcription factor. (520 aa)    
Predicted Functional Partners:
TFE3
Transcription factor binding to IGHM enhancer 3.
   
 0.974
TFEB
Transcription factor EB.
   
 0.955
ENSNVIP00000015363
Exportin 1.
     
 0.943
MAPK3
Mitogen-activated protein kinase 3.
    
 0.930
MAPK1
Mitogen-activated protein kinase 1.
    
 0.930
ENSNVIP00000008351
Lymphoid enhancer binding factor 1.
    
 0.918
ENSNVIP00000005145
Tyrosinase.
   
 0.905
KIT
KIT proto-oncogene, receptor tyrosine kinase.
   
 0.904
TNFSF11
TNF superfamily member 11.
     
 0.859
RPS6KA1
Ribosomal protein S6 kinase A1.
    
 0.850
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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