Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIK2Salt inducible kinase 2. (891 aa)    
Predicted Functional Partners:
CRTC2
CREB regulated transcription coactivator 2.
    
 0.972
ENSNVIP00000022074
annotation not available
    
 0.972
CRTC3
CREB regulated transcription coactivator 3.
    
 0.956
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
   
 0.892
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
   
 0.892
PPP2R2C
Protein phosphatase 2 regulatory subunit Bgamma.
   
  0.871
VCP
Valosin containing protein.
    
 
 0.856
YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta.
    
 0.773
ENSNVIP00000001057
General transcription factor IIF subunit 2.
     
  0.674
PPP2R2D
Protein phosphatase 2 regulatory subunit Bdelta.
   
  0.662
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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