Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD6Ankyrin repeat domain 6. (727 aa)    
Predicted Functional Partners:
SMC2
Structural maintenance of chromosomes 2.
    
   0.748
APP
Amyloid beta precursor protein.
    
 0.682
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.638
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.638
PRICKLE2
Prickle planar cell polarity protein 2.
    
 0.621
PRICKLE3
Prickle planar cell polarity protein 3.
    
 0.618
ENSNVIP00000016225
annotation not available
    
 0.616
DVL1
Dishevelled segment polarity protein 1.
    
 0.613
PRICKLE1
Prickle planar cell polarity protein 1.
    
 0.609
RELB
RELB proto-oncogene, NF-kB subunit.
   
 0.607
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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