Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000002657Transmembrane protein 74. (303 aa)    
Predicted Functional Partners:
LRCH4
Leucine rich repeats and calponin homology domain containing 4.
      
 0.566
WDR20
WD repeat domain 20.
      
 0.553
TM4SF5
Transmembrane 4 L six family member 5.
      
 0.553
CDADC1
Cytidine and dCMP deaminase domain containing 1.
      
 0.550
ENSNVIP00000029860
annotation not available
      
 0.540
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.535
ATG16L2
Autophagy related 16 like 2.
    
 
 0.502
PRRG4
Proline rich and Gla domain 4.
      
 0.496
PAK1IP1
PAK1 interacting protein 1.
      
 0.488
DRAM1
DNA damage regulated autophagy modulator 1.
      
 0.487
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (40%) [HD]