Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRSepiapterin reductase. (267 aa)    
Predicted Functional Partners:
PAH
Phenylalanine hydroxylase.
   
 
 0.969
QDPR
Quinoid dihydropteridine reductase.
   
 0.955
ENSNVIP00000002172
annotation not available
     
 0.936
TPH2
Tryptophan hydroxylase 2.
   
 
 0.925
TPH1
Tryptophan hydroxylase 1.
   
 
 0.925
ENSNVIP00000009764
annotation not available
   
 
 0.915
ENSNVIP00000012522
annotation not available
   
 0.898
AKR1B1
Aldo-keto reductase family 1 member B.
   
 0.861
PRKG2
Protein kinase cGMP-dependent 2.
   
 0.836
AKR1E2
Aldo-keto reductase family 1 member E2.
   
 0.817
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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