Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASP2Caspase 2. (452 aa)    
Predicted Functional Partners:
PIDD1
P53-induced death domain protein 1.
    
 0.995
ENSNVIP00000008759
annotation not available
    
 0.948
ENSNVIP00000008764
CASP2 and RIPK1 domain containing adaptor with death domain.
    
 0.948
CASP3
Caspase 3.
    
 0.936
ENSNVIP00000016365
annotation not available
   
 0.906
ENSNVIP00000029921
annotation not available
   
 0.906
CASP10
Caspase 10.
   
 0.844
ENSNVIP00000010832
annotation not available
    
 0.838
CASP8
Caspase 8.
   
 0.822
XIAP
X-linked inhibitor of apoptosis.
   
 0.790
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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