Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOX10SRY-box transcription factor 10. (470 aa)    
Predicted Functional Partners:
PAX3
Paired box 3.
   
 0.930
PAX7
Paired box 7.
   
 0.897
SOX8
SRY-box transcription factor 8.
   
 
 0.867
FBXW7
F-box and WD repeat domain containing 7.
    
 
 0.860
MBP
Myelin basic protein.
   
 0.849
ENSNVIP00000014997
Early growth response 2.
    
 0.842
EP300
E1A binding protein p300.
    
 0.816
PLP1
Proteolipid protein 1.
   
  
 0.788
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
 0.786
RUNX1
RUNX family transcription factor 1.
   
 0.786
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (18%) [HD]