STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.998
EGFR
Epidermal growth factor receptor.
    
 0.995
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.992
ENSNVIP00000009278
annotation not available
    
 0.990
PTK2
Protein tyrosine kinase 2.
    
 0.989
SHC1
SHC adaptor protein 1.
    
 0.986
SHC3
SHC adaptor protein 3.
    
 0.985
EPS8
Epidermal growth factor receptor pathway substrate 8.
   
 
 0.981
NCK1
NCK adaptor protein 1.
    
 0.976
ENSNVIP00000001458
KRAS proto-oncogene, GTPase.
   
 0.972
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.