Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASTOR1Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa)    
Predicted Functional Partners:
WDR59
WD repeat domain 59.
    
 0.996
WDR24
WD repeat domain 24.
    
 0.996
ENSNVIP00000025778
Meiosis regulator for oocyte development.
    
 0.996
ENSNVIP00000007693
annotation not available
  
0.993
SEH1L
SEH1 like nucleoporin.
    
 0.981
ENSNVIP00000031364
SEC13 homolog, nuclear pore and COPII coat complex component.
    
 0.975
SESN2
Sestrin 2.
    
 
 0.972
ENSNVIP00000018969
Zinc finger C2HC-type containing 1A.
    
 
 0.925
SESN1
Sestrin 1.
    
 0.839
SESN3
Sestrin 3.
    
 0.803
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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