Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP4Insulin like growth factor binding protein 4. (258 aa)    
Predicted Functional Partners:
ENSNVIP00000013151
Insulin like growth factor 1.
   
 0.991
IGF2
Insulin like growth factor 2.
    
 0.938
IGFBP1
Insulin like growth factor binding protein 1.
   
 
 0.842
PAPPA
Pappalysin 1.
     
 0.772
IGFBP3
Insulin like growth factor binding protein 3.
   
 
 0.664
PAPPA2
Pappalysin 2.
     
 0.544
FBLN2
Fibulin 2.
      
 0.492
ENSNVIP00000019435
annotation not available
      
 0.440
IGFALS
Insulin like growth factor binding protein acid labile subunit.
      
 0.417
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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