Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LDLRLow density lipoprotein receptor. (857 aa)    
Predicted Functional Partners:
APOB
Apolipoprotein B.
    
 0.996
MYLIP
Myosin regulatory light chain interacting protein.
    
 0.992
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.990
APOE
Apolipoprotein E.
    
 0.986
DAB1
DAB adaptor protein 1.
    
 0.934
RELN
Reelin.
    
 0.929
DAB2
DAB adaptor protein 2.
    
 0.920
LRPAP1
LDL receptor related protein associated protein 1.
    
 0.919
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
   
  
 0.903
SREBF2
Sterol regulatory element binding transcription factor 2.
   
 
 0.886
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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