Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DTX3Deltex E3 ubiquitin ligase 3. (354 aa)    
Predicted Functional Partners:
PARP14
poly(ADP-ribose) polymerase family member 14.
   
 0.902
PARP9
poly(ADP-ribose) polymerase family member 9.
   
 0.855
FAM162A
Family with sequence similarity 162 member A.
   
 0.855
NOTCH1
Notch receptor 1.
    
 0.739
DTX1
Deltex E3 ubiquitin ligase 1.
    
 0.729
NOTCH4
Notch receptor 4.
    
  0.711
NUDCD1
NudC domain containing 1.
    
   0.650
RBM43
RNA binding motif protein 43.
   
   0.642
DTX2
Deltex E3 ubiquitin ligase 2.
    
  0.555
DTX4
Deltex E3 ubiquitin ligase 4.
    
  0.555
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.