STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000003222Insulin induced gene 2. (225 aa)    
Predicted Functional Partners:
SCAP
SREBF chaperone.
   
 0.880
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase.
   
 
 0.854
CHAF1B
Chromatin assembly factor 1 subunit B.
    
 
 0.776
AMFR
Autocrine motility factor receptor.
    
 
 0.740
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.676
ENSNVIP00000027981
annotation not available
   
 0.676
ORC3
Origin recognition complex subunit 3.
    
   0.669
ENSNVIP00000028127
Origin recognition complex subunit 5.
    
   0.669
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
   
  
 0.619
ENSNVIP00000024373
Proliferating cell nuclear antigen.
   
 
 0.599
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.