Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP00000003284Leucine rich glioma inactivated 1. (557 aa)    
Predicted Functional Partners:
ADAM22
ADAM metallopeptidase domain 22.
   
 0.980
ADAM11
ADAM metallopeptidase domain 11.
   
 0.926
ADAM23
ADAM metallopeptidase domain 23.
   
 0.879
DLG4
Discs large MAGUK scaffold protein 4.
   
 0.851
DPP10
Dipeptidyl peptidase like 10.
   
  
 0.789
AMPH
Amphiphysin.
   
  
 0.780
DPP6
Dipeptidyl peptidase like 6.
   
  
 0.773
DNER
Delta/notch like EGF repeat containing.
   
  
 0.763
ENSNVIP00000000776
G protein-coupled receptor 37.
   
  
 0.758
ZIC4
Zic family member 4.
   
  
 0.756
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (18%) [HD]