Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRG3Neuregulin 3. (722 aa)    
Predicted Functional Partners:
ERBB4
Erb-b2 receptor tyrosine kinase 4.
     
 0.895
NRG2
Neuregulin 2.
     
 0.889
NRG1
Neuregulin 1.
     
 0.886
ERBB3
Erb-b2 receptor tyrosine kinase 3.
     
 0.787
ERBB2
Erb-b2 receptor tyrosine kinase 2.
     
 0.627
EGFR
Epidermal growth factor receptor.
     
 0.627
ENSNVIP00000022794
Spindle and kinetochore associated complex subunit 3.
      
 0.432
NDC80
NDC80 kinetochore complex component.
      
 0.417
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
      
 0.403
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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