Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F7E2F transcription factor 7. (899 aa)    
Predicted Functional Partners:
E2F8
E2F transcription factor 8.
   
 0.980
E2F1
E2F transcription factor 1.
   
 0.743
TP53
Tumor protein p53.
    
 0.736
KIF11
Kinesin family member 11.
  
  
 0.726
CDC6
Cell division cycle 6.
   
  
 0.673
ENSNVIP00000020897
annotation not available
   
  
 0.673
NF1
Neurofibromin 1.
   
  
 0.657
TFDP1
Transcription factor Dp-1.
    
 
 0.621
NAV3
Neuron navigator 3.
   
  
 0.616
HINFP
Histone H4 transcription factor.
      
 0.598
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.