STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF1RInsulin like growth factor 1 receptor. (1367 aa)    
Predicted Functional Partners:
ENSNVIP00000013151
Insulin like growth factor 1.
    
 0.999
INSR
Insulin receptor.
  
0.992
INS
Insulin.
    
 0.981
GRB10
Growth factor receptor bound protein 10.
    
 0.981
ENSNVIP00000009722
annotation not available
    
 0.979
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.979
MDM2
MDM2 proto-oncogene.
    
 0.976
IRS4
Insulin receptor substrate 4.
   
 0.976
ENSNVIP00000025169
annotation not available
    
 0.972
IRS1
Insulin receptor substrate 1.
   
 0.971
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: medium (46%) [HD]