PDX1 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PDX1

Pancreatic and duodenal homeobox 1. (283 aa)

Predicted Functional Partners:

PRKACA

0.887

PRKACB

0.887

GCK

0.839

VPS9D1

0.827

NAV3

0.825

ENSNVIP00000009722

0.813

INS

0.813

FOXA2

0.773

MAFA

0.771

MAFB

0.771

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNVIP00000009722	FOXA2	ENSNVIP00000009722	ENSNVIP00000008724	annotation not available	Forkhead box A2.	0.488
ENSNVIP00000009722	GCK	ENSNVIP00000009722	ENSNVIP00000027326	annotation not available	Glucokinase.	0.488
ENSNVIP00000009722	MAFA	ENSNVIP00000009722	ENSNVIP00000013529	annotation not available	MAF bZIP transcription factor A.	0.511
ENSNVIP00000009722	MAFB	ENSNVIP00000009722	ENSNVIP00000016372	annotation not available	MAF bZIP transcription factor B.	0.511
ENSNVIP00000009722	PDX1	ENSNVIP00000009722	ENSNVIP00000003571	annotation not available	Pancreatic and duodenal homeobox 1.	0.813
ENSNVIP00000009722	PRKACA	ENSNVIP00000009722	ENSNVIP00000008777	annotation not available	Protein kinase cAMP-activated catalytic subunit alpha.	0.415
ENSNVIP00000009722	PRKACB	ENSNVIP00000009722	ENSNVIP00000011560	annotation not available	Protein kinase cAMP-activated catalytic subunit beta.	0.415
FOXA2	ENSNVIP00000009722	ENSNVIP00000008724	ENSNVIP00000009722	Forkhead box A2.	annotation not available	0.488
FOXA2	INS	ENSNVIP00000008724	ENSNVIP00000009743	Forkhead box A2.	Insulin.	0.488
FOXA2	PDX1	ENSNVIP00000008724	ENSNVIP00000003571	Forkhead box A2.	Pancreatic and duodenal homeobox 1.	0.773
GCK	ENSNVIP00000009722	ENSNVIP00000027326	ENSNVIP00000009722	Glucokinase.	annotation not available	0.488
GCK	INS	ENSNVIP00000027326	ENSNVIP00000009743	Glucokinase.	Insulin.	0.488
GCK	PDX1	ENSNVIP00000027326	ENSNVIP00000003571	Glucokinase.	Pancreatic and duodenal homeobox 1.	0.839
INS	FOXA2	ENSNVIP00000009743	ENSNVIP00000008724	Insulin.	Forkhead box A2.	0.488
INS	GCK	ENSNVIP00000009743	ENSNVIP00000027326	Insulin.	Glucokinase.	0.488
INS	MAFA	ENSNVIP00000009743	ENSNVIP00000013529	Insulin.	MAF bZIP transcription factor A.	0.511
INS	MAFB	ENSNVIP00000009743	ENSNVIP00000016372	Insulin.	MAF bZIP transcription factor B.	0.511
INS	PDX1	ENSNVIP00000009743	ENSNVIP00000003571	Insulin.	Pancreatic and duodenal homeobox 1.	0.813
INS	PRKACA	ENSNVIP00000009743	ENSNVIP00000008777	Insulin.	Protein kinase cAMP-activated catalytic subunit alpha.	0.415
INS	PRKACB	ENSNVIP00000009743	ENSNVIP00000011560	Insulin.	Protein kinase cAMP-activated catalytic subunit beta.	0.415