Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLRP12NLR family pyrin domain containing 12. (1027 aa)    
Predicted Functional Partners:
ENSNVIP00000032327
PYD and CARD domain containing.
   
 0.965
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.899
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.890
ENSNVIP00000022228
Interleukin 1 beta.
   
 0.745
MAVS
Mitochondrial antiviral signaling protein.
    
 0.709
BRCC3
BRCA1/BRCA2-containing complex subunit 3.
    
 0.669
NEK7
NIMA related kinase 7.
    
 0.668
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
  0.656
NEK6
NIMA related kinase 6.
    
 0.648
TXNIP
Thioredoxin interacting protein.
    
 0.636
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.