Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSNVIP000000036825-hydroxytryptamine receptor 2B. (481 aa)    
Predicted Functional Partners:
ENSNVIP00000011653
5-hydroxytryptamine receptor 2A.
  
0.960
HTR2C
5-hydroxytryptamine receptor 2C.
    
 
0.884
CACNA1F
Calcium voltage-gated channel subunit alpha1 F.
     
  0.882
CACNA1S
Calcium voltage-gated channel subunit alpha1 S.
     
  0.882
GNA14
G protein subunit alpha 14.
    
 0.854
GNA15
G protein subunit alpha 15.
    
  0.839
GNA11
G protein subunit alpha 11.
    
 0.810
GNAQ
G protein subunit alpha q.
    
 0.810
CACNA1C
Calcium voltage-gated channel subunit alpha1 C.
     
  0.761
CACNA1D
Calcium voltage-gated channel subunit alpha1 D.
     
  0.761
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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