STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THRAThyroid hormone receptor alpha. (511 aa)    
Predicted Functional Partners:
NCOR1
Nuclear receptor corepressor 1.
    
 0.969
MED1
Mediator complex subunit 1.
    
 0.964
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
   
 0.964
NCOA1
Nuclear receptor coactivator 1.
    
 0.960
ENSNVIP00000022494
annotation not available
   
 0.944
THRB
Thyroid hormone receptor beta.
  
  
0.942
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.940
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
    
  0.939
ENSNVIP00000025169
annotation not available
   
 0.936
NCOA3
Nuclear receptor coactivator 3.
    
 0.932
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.