Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PARP8poly(ADP-ribose) polymerase family member 8. (854 aa)    
Predicted Functional Partners:
GPI
Glucose-6-phosphate isomerase.
  
 0.953
ENO4
Enolase 4.
  
 0.905
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
 
 0.901
ENO1
Enolase 1.
  
 0.881
ENO3
Enolase 3.
  
 0.881
ENSNVIP00000029463
Bisphosphoglycerate mutase.
  
 0.881
ENO2
Enolase 2.
  
 0.881
TPI1
Triosephosphate isomerase 1.
  
 
 0.874
PGK2
Phosphoglycerate kinase 2.
  
 0.864
PGK1
Phosphoglycerate kinase 1.
  
 0.864
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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