Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS6Transmembrane serine protease 6. (808 aa)    
Predicted Functional Partners:
HJV
Hemojuvelin BMP co-receptor.
    
 
 0.958
DCN
Decorin.
   
 0.803
HAMP
Hepcidin antimicrobial peptide.
   
  
 0.761
BOP1
BOP1 ribosomal biogenesis factor.
      
 0.673
HFE
Homeostatic iron regulator.
     
 0.655
TFR2
Transferrin receptor 2.
   
  
 0.622
BMP6
Bone morphogenetic protein 6.
      
 0.552
TFRC
Transferrin receptor.
   
  
 0.543
ENSNVIP00000026143
Dihydrolipoamide dehydrogenase.
    
   0.517
SLC25A28
Solute carrier family 25 member 28.
      
 0.514
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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