Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PROS1Protein S. (675 aa)    
Predicted Functional Partners:
MERTK
MER proto-oncogene, tyrosine kinase.
   
 0.974
F5
Coagulation factor V.
   
 0.962
GGCX
Gamma-glutamyl carboxylase.
   
 0.949
TYRO3
TYRO3 protein tyrosine kinase.
    
 0.946
AXL
AXL receptor tyrosine kinase.
    
 0.929
ENSNVIP00000015139
Complement component 4 binding protein beta.
    
 0.900
ENSNVIP00000030788
annotation not available
   
 0.880
ENSNVIP00000012402
Complement C5.
   
 
 0.864
ENSNVIP00000015046
annotation not available
   
 0.807
ENSNVIP00000030625
annotation not available
   
 0.807
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (16%) [HD]