STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICALMPhosphatidylinositol binding clathrin assembly protein. (620 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.965
ITSN2
Intersectin 2.
    
 0.942
AP2M1
Adaptor related protein complex 2 subunit mu 1.
   
 0.903
AP2A1
Adaptor related protein complex 2 subunit alpha 1.
   
 0.902
CLTCL1
Clathrin heavy chain like 1.
   
 0.894
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 0.890
CLTB
Clathrin light chain B.
    
 0.882
CLTC
Clathrin heavy chain.
   
 0.879
ITSN1
Intersectin 1.
    
 0.870
HIP1R
Huntingtin interacting protein 1 related.
    
 0.856
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.