STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX2Deltex E3 ubiquitin ligase 2. (619 aa)    
Predicted Functional Partners:
NOTCH2
Notch receptor 2.
     
 0.885
NOTCH3
Notch receptor 3.
     
 0.882
NOTCH4
Notch receptor 4.
     
 0.860
NOTCH1
Notch receptor 1.
    
 0.838
ENSNVIP00000020149
annotation not available
     
 0.768
DTX1
Deltex E3 ubiquitin ligase 1.
    
  0.747
DTX3L
Deltex E3 ubiquitin ligase 3L.
    
 0.701
ITCH
Itchy E3 ubiquitin protein ligase.
     
 0.650
DTX3
Deltex E3 ubiquitin ligase 3.
    
  0.555
TBK1
TANK binding kinase 1.
    
 0.445
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.