STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLI2GLI family zinc finger 2. (1471 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.997
SPOP
Speckle type BTB/POZ protein.
   
 0.979
SPOPL
Speckle type BTB/POZ protein like.
   
 0.973
KIF7
Kinesin family member 7.
    
 0.957
KIF3A
Kinesin family member 3A.
    
 0.952
GLI1
GLI family zinc finger 1.
   
 0.951
SMO
Smoothened, frizzled class receptor.
    
 0.941
FBXW11
F-box and WD repeat domain containing 11.
    
 0.938
PTCH1
Patched 1.
   
 0.934
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
 0.933
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.