Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAP1ArfGAP with dual PH domains 1. (374 aa)    
Predicted Functional Partners:
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
    
 0.653
CTTN
Cortactin.
    
   0.605
NCL
Nucleolin.
    
 
 0.540
RPS6KC1
Ribosomal protein S6 kinase C1.
      
 0.484
GAK
Cyclin G associated kinase.
   
 
 0.477
RPS6KL1
Ribosomal protein S6 kinase like 1.
      
 0.471
ENSNVIP00000024215
UTP6 small subunit processome component.
      
 0.470
COPRS
Coordinator of PRMT5 and differentiation stimulator.
      
 0.464
ENSNVIP00000024436
annotation not available
      
 0.455
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.454
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.