Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1. (3008 aa)    
Predicted Functional Partners:
VANGL2
VANGL planar cell polarity protein 2.
    
 0.851
VANGL1
VANGL planar cell polarity protein 1.
    
 0.851
FZD6
Frizzled class receptor 6.
    
 0.789
DVL2
Dishevelled segment polarity protein 2.
     
 0.755
TCF20
Transcription factor 20.
      
 0.741
FZD3
Frizzled class receptor 3.
    
 0.693
PTK7
Protein tyrosine kinase 7 (inactive).
   
  
 0.659
ZDHHC8
Zinc finger DHHC-type containing 8.
      
 0.640
PRICKLE1
Prickle planar cell polarity protein 1.
   
 0.638
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3.
      
 0.636
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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