Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSPB1Heat shock protein family B (small) member 1. (207 aa)    
Predicted Functional Partners:
MAPKAPK2
MAPK activated protein kinase 2.
    
 0.978
MAPKAPK5
MAPK activated protein kinase 5.
    
 0.971
MAPKAPK3
MAPK activated protein kinase 3.
    
 0.966
CRYAB
Crystallin alpha B.
   
 0.953
BAG3
BCL2 associated athanogene 3.
   
 
 0.892
TP53
Tumor protein p53.
    
 
 0.884
DAXX
Death domain associated protein.
    
 
 0.863
ENSNVIP00000008002
Alpha-crystallin A chain.
   
 0.850
ENSNVIP00000029497
Elongation factor Tu GTP binding domain containing 2.
    
 
 0.831
SF3B3
Splicing factor 3b subunit 3.
    
   0.828
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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